High performance domain models
Udi has an interesting presentation that I recommend that you go through. He is going to present it at Tech Ed (Thu Nov 8 13:30 - 14:45 Room 117).
Most of the ideas are familiar to me because I have spoken to him about them before, but it represent new concepts to most people. I would preface his suggestion with the usual warning about designing for performance. Udi's points are about big systems, so consider if they are appropriate to your scenario first.
A pal of mine once told me that he designs systems for an order of magnitude increase in the requirements. So a system that works for a hundred users should also scale to a thousand users (additional hardware, maybe, but the architecture should hold), but going beyond that will require more than just throwing hardware at the issue.
This sounds like a good rule of the thumb.
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